I wore Sealskinz a few years ago (apparently the deisgn has changed since then) with mixed results. In winter I appreciated the extra warmth, but the moisture retention was almost hazardous in extreme cold; and to be honest I never found them to be especially comfortable. Mind you, they were much cheaper than usual because I picked up a pair of white ones at a heavy discount. Really practical outdoor colour, white...
For general hiking I gave up on waterproof socks, finding that good wool socks kept my feet much more comfortable when wet not least because any water that gets inside Sealskinz tends to stay there. If I was standing around in wet conditions then perhaps I'd reconsider, but on the other hand I expect I'd favour a pair of wellies or Bean boots instead. For the price of one pair of Sealskinz you can get two pairs of Smartwool. No contest for my purposes.