Since bear's garlic has become so popular, many people have tried to collect the plant in the wild. Several cases of poisoning have been reported in the last years, as there are a few toxic plants with roughly similar leaves, particularly lily of the valley (Convallaria majus, Convallariaceae/Asparaginales) and autumn crocus (meadow saffron, naked ladies, Colchicum autumnale, Colchicaceae/Liliales). Both plants do not show even traces of garlic odour, and similarities are in the best case superficial, or even non-existent.
Lily of the valley contains cardioactive glycosides with physiological effects similar to digitalis, but their concentration in the leaves is comparatively small, and, as a consequence, live-threatening conditions due to poisoning occur but rarely. The situation is different with autumn crocus: All plant parts are rich in colchicine, a highly toxic alkaloid. Colchicine poisoning takes lethal course very often. Autumn crocus flowers have also been confused with saffron flowers by the inexperienced.